foxo4 dri senolytic 2023 2024 Targeting Cellular Senescence in Aging and Age-Related Diseases: Challenges, Considerations, and the Emerging Role of and Senomorphic Therapies The disordered p53 transactivation domain
The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications Frontiers FOXO4 DRI regulates endothelial cell senescence via the P53 signaling pathway FOXO4 DRI regulates endothelial cell senescence via the P53 signaling pathway PMC CHK2 USP37 axis stabilizes FOXO4 to sustain senescence and evade apoptosis PNAS
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