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Identifying biomarkers of clinically significant metabolic subtypes of autism could improve understanding of its underlying pathophysiology and potentially lead to more targeted interventions

When administered in the drinking-water for approximately 7 weeks, aspartame increased fasting insulin levels without changes in lipid metabolism (Janssens et al., 2017) or it increased glucose levels with alteration in lipid metabolism (Lebda et al., 2017b)

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The CST IV subtypes further clarify that IV-A and IV-B are the predominant forms and are associated with elevated vaginal pH and higher Nugent scores in African and Hispanic women, whereas IV-C is less prevalent 61