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Stock Index Portfolio Initial Investment Grade Municipal Trust Investment Grade Municipal Trust Investment Grade Income Trust Investment Grade Income Trust Investment Grade Municipal Trust Invesco Unit Tr Investment Grade Income Tr Investment Grade Income Trust Investment Grade Income Trust Western Asset Institutional Government Reserves Institutional Shares Van Eck International Investors Gold Fund I Select 10 Industrial Portfolio 2019-6 (Invesco Unit Trusts Federated Intermediate Corporate Bond Fd Svc Shs Van Eck Funds - International Investors Gold Class A Van Eck International Investors Gold Fund Cl Y Insured Municipals Income Trust Investment Grade Municipal Trust Investment Grade Municipal Trust North Square Global Resources & Infrastructure Fund Class A North Square Global Resources & Infrastructure Fund Class I American Funds Conservative Growth and Income Portfolio - Class A American Funds Conservative Growth and Income Portfolio - Class C American Funds Conservative Growth and Income Portfolio - Class F-3 American Funds Conservative Growth and Income Portfolio - Class F-2 American Funds Conservative Growth and Income Portfolio - Class F-1 Internet UltraSector ProFund PREFERRED-PLUS - Class A Internet UltraSector ProFund Invesco Unit Tr Investment Grade Income Tr Ivy Natural Resources Fund Class N Catalyst Insider Buying Fd Cl A Catalyst Insider Buying Fd Cl C Catalyst Insider Buying Fund Class I Invesco Oppenheimer International Small-Mid Company Fund Class R5 Insured Municipals Income Trust Insured Municipals Income Trust Insured Municipals Income Trust Insured Municipals Income Trust Srs 662 Closed-End Strategy: Master Income Portfolio 2019-1 (Invesco Unit Trusts Insured Municipals Income Trust Srs 668 Columbia Strategic Municipal Income Fund Class A Voya International Index Portfolio Service Forester Discovery Fund Investment Grade Income Trust Columbia Dividend Opportunity Fund Class A Investment Grade Corporate Trust Investment Grade Corporate Trust Investment Grade Municipal Trust Intermediate Srs 44 Investment Grade Municipal Trust Investment Grade Municipal Trust Investment Grade Income Trust Investment Grade Income Trust Investment Grade Income Trust Investment Grade Corporate Trust Investment Grade Income Trust Investment Grade Income Trust Investment Grade Income Tr 20+ Year Srs 41 Invesco Government Money Market Fund Class R6 Pioneer International Equity Fund Class Y New World Leaders Portfolio 2019-1 (Invesco Unit Trusts New World Leaders Portfolio 2019-3 (Invesco Unit Trusts New World Leaders Portfolio 2019-4 (Invesco Unit Trusts Pioneer Disciplined Growth Fund Class Y Invesco Oppenheimer Main Street All Cap Fund Class R6 ICON Flexible Bond Fund Class A ICON Flexible Bond Fund Class C ICON Flexible Bond Fund Class S ICON Risk-Managed Equity Fund Class A ICON Risk-Managed Equity Fund Class C ICON Risk-Managed Equity Fund Class S ICON Equity Income Fund - Class C Shares ICON Equity Income Fund Class S AlphaCentric Income Opportunities Fund - Class A AlphaCentric Income Opportunities Fund - Class C AlphaCentric Income Opportunities Fund - Class I VY Oppenheimer Global Portfolio S2 Invesco Oppenheimer Gold & Special Minerals Fund Class R5 Invesco Oppenheimer Intermediate Term Municipal Fund Class R6 Defensive Equity & Income Portfolio 2020-1 (Invesco Unit Trusts ICON Long/Short Fund - Class C Shares Invesco Oppenheimer Limited-Term Government Fund Class R5 Invesco Oppenheimer Limited-Term Bond Fund Class R5 ICON Long/Short Fund Cl S Invesco Oppenheimer Municipal Fund Class R6 Preferred Opportunity Portfolio 2019-4 (Invesco Unit Trusts Policy Opportunities Portfolio 2019-1 (Invesco Unit Trusts Invesco Oppenheimer Rochester AMT-Free Municipal Fund Class R6 Invesco Oppenheimer Rochester California Municipal Fund Class R6 Invesco Oppenheimer Rochester High Yield Municipal Fund Class R5 Invesco Oppenheimer Rochester New Jersey Municipal Fund Class R6 Invesco Oppenheimer Rochester Limited Term California Municipal Fund Class R6 Invesco Oppenheimer Rochester Limited Term New York Municipal Fund Class R6 Invesco Oppenheimer Rochester AMT-Free New York Municipal Fund Class R6 Invesco Oppenheimer Rochester Pennsylvania Municipal Fund Class R6 Invesco Oppenheimer Rochester Municipals Fund Class R6 Invesco Oppenheimer Rochester High Yield Municipal Fund Class R6 Voya Global Bond Portfolio Adviser Voya Global Bond Portfolio Initial Voya Global Bond Portfolio Service Invesco Intermediate Bond Factor Fund Class R5 ESG Opportunity Portfolio 2019-1 (Invesco Unit Trusts Invesco Comstock Select Fund Class R5 Catalyst/Stone Beach Income Opportunity Fund Class A Catalyst/Stone Beach Income Opportunity Fund Class C Catalyst/Stone Beach Income Opportunity Fund Class I Voya Global Perspectives Portfolio Adviser Policy Opportunities Portfolio 2018-3 (Invesco Unit Trusts Wells Fargo Real Return Fund - Class A Wells Fargo Real Return Fund - Class C Wells Fargo Real Return Fund - Admin Wells Fargo Real Return Fund-R6 Wells Fargo Real Return Fund-I ICON Emerging Markets Fund - Class A DIVIDEND PERFORMERS - Class I Voya Large Cap Value Portfolio Class ADV Voya LargeCap Value Portfolio Initial Preferred Opportunity Portfolio 2018-3 (Invesco Unit Trusts Voya LargeCap Value Portfolio Service Voya LargeCap Value Portfolio S2 ETF Allocation Portfolio 2018-4 (Invesco Unit Trusts Poplar Forest Cornerstone Fund - Institutional Class Victory INCORE Fund for Income Class A Preferred Opportunity Portfolio 2019-2 (Invesco Unit Trusts Preferred Opportunity Portfolio 2018-1 (Invesco Unit Trusts Poplar Forest Partners Fund Insti Class Preferred Opportunity Portfolio 2018-2 (Invesco Unit Trusts VY PIMCO High Yield Portfolio Service Voya Intermediate Bond Portfolio I VY PIMCO High Yield Portfolio Initial Select 10 Industrial Portfolio 2020-1 (Invesco Unit Trusts Voya Global Perspectives Portfolio Initial Voya Intermediate Bond Portfolio Service Voya Index Plus LargeCap Portfolio Initial Voya Index Plus LargeCap Portfolio Service Voya Liquid Assets Portfolio Initial Voya Index Plus MidCap Portfolio Initial Voya Index Plus MidCap Portfolio Service Ivy PineBridge High Yield Fund Class A Quality Municipal Income Trust Invesco Multi Asset Income Fund Class R5 Ivy PineBridge High Yield Fund Class I Ivy PineBridge High Yield Fund Class N PowerPicks Portfolio 2020-1 (Invesco Unit Trusts Ivy PineBridge High Yield Fund Class R Ivy Emerging Markets Equity Fund Class A Ivy Emerging Markets Equity Fund Class B Ivy Emerging Markets Equity Fund Class C Ivy Emerging Markets Equity Fund Class E Ivy Emerging Markets Equity Fund Class I Preferred Opportunity Portfolio 2019-3 (Invesco Unit Trusts Preferred Opportunity Portfolio 2019-1 (Invesco Unit Trusts Preferred Opportunity Portfolio 2018-4 (Invesco Unit Trusts Ivy Emerging Markets Equity Class T Ivy Emerging Markets Equity Fund Class Y PowerPicks Portfolio 2020-2 (Invesco Unit Trusts PowerPicks Portfolio 2019-4 (Invesco Unit Trusts PREFERRED-PLUS - Class I Invesco Premier Portfolio Institutional Class Shares Ivy ProShares S&P 500 Bond Index Fund Class E Ivy ProShares S&P 500 Bond Index Fund Class I Ivy ProShares S&P 500 Bond Index Fund Class N Ivy ProShares S&P 500 Bond Index Fund Class R Ivy ProShares S&P 500 Bond Index Fund Class T IPS Strategic Capital Absolute Return Fund Institutional Class Pinnacle Sherman Multi-Strategy Core Fund - Class I Shares Voya Index Plus SmallCap Portfolio Initial Voya Global Perspectives Portfolio Service Voya Index Plus SmallCap Portfolio Service Pinnacle TrendRating Innovative Equity Fund-Class I Premier Portfolio Private Invt Cl Shs Turnaround Strategy Portfolio 2020-1 (Invesco Unit Trusts Premier Portfolio Personal Invt Cl Shs S&P PowerPicks Portfolio 2019-1 (Invesco Unit Trusts VY PIMCO High Yield Portfolio Adviser VY PIMCO High Yield Portfolio S2 Investors Quality Tax-Exempt Trust Srs 182 Quality Municipal Income Trust Quality Municipals Income Trust 72nd Limited Maturity Srs ADT 1917 Income Quality Covered Call Portfolio Series 2019-1Q Infinity Q Diversified Alpha Fund Investor Class Infinity Q Diversified Alpha Fund Institutional Class Quality Municipal Income Trust Quality Municipal Income Trust Invesco Unit Tr Investors Quality Tax-Exempt Tr Srs 178 Investors Quality Tax-Exempt Trust Srs 180 Investors Quality Tax-Exempt Tr Srs 176 Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipals Income Tr 68th Limited Maturity Srs Quality Municipal Income Trust Quality Municipals Income Trust 71st Limited Maturity Series Invesco Unit Tr Quality Municipals Income Tr 69th Limited Maturity Srs Quality Municipal Income Trust Quality Municipals Income Trust 73rd Limited Maturity Series Investors' Quality Municipal Trust Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipals Income Trust 79th Limited Maturity Series ACR International Quality Return (IQR) Fund - Class A ACR International Quality Return (IQR) Fund - Class I Investors Quality Tax-Exempt Tr Srs 175 Investors Quality Tax-Exempt Trust Srs 174 Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Investors' Quality Tax-Exempt Trust Investors' Quality Tax-Exempt Trust Quality Municipal Income Trust Invesco Unit Tr Investors Quality Tax-Exempt Tr Srs 177 Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Invesco Unit Tr Quality Municipals Income Tr 70th Limited Maturity Srs Quality Municipal Income Trust Investors Quality Tax-Exempt Trust Srs 179 Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust Quality Municipal Income Trust CIM Real Assets & Credit Fund - Class I Ivy Pictet Targeted Return Bond Fund Class A Ivy Pictet Targeted Return Bond Fund Class C Ivy Pictet Targeted Return Bond Fund Class I Ivy Pictet Targeted Return Bond Fund Class N Ivy Pictet Targeted Return Bond Fund Class Y Voya Retirement Conservative Portfolio Adviser Voya Russell Small Cap Index Portfolio S2 Voya Retirement Conservative Portfolio Initial Bernstein International Small Cap Portfolio - SCB Investment Grade Corporate Trust Premier Portfolio Resource Cl Shs AB International Small Cap Portfolio - ADV AB International Small Cap Portfolio - Z iShares Russell 3000 ETF 529 Portfolio Cl AG iShares Russell 3000 ETF 529 Portfolio Cl C iShares Russell 3000 ETF 529 Portfolio Class I Ivy LaSalle Global Real Estate Fund Class A Ivy LaSalle Global Real Estate Fund Class B Ivy LaSalle Global Real Estate Fund Class C Ivy Securian Real Estate Securities Fund Class E REIT Income Portfolio 2019-2 (Invesco Unit Trusts REIT Income Portfolio 2018-4 (Invesco Unit Trusts REIT Income Portfolio 2018-3 (Invesco Unit Trusts Ivy Securian Real Estate Securities Fund Class I Ivy Lasalle Global Real Estate Class N Ivy LaSalle Global Real Estate Fund Class R Ivy LaSalle Global Real Estate Fund Class I Ivy LaSalle Global Real Estate Fund Class Y Cohen & Steers International Realty Fund Class A Cohen & Steers International Realty Fund Class C Cohen & Steers International Realty Fund Cohen & Steers International Realty Fund Class I Cohen & Steers International Reality Fund Cohen & Steers International Reality Fund Ivy Small Cap Growth Fund Class N VY Clarion Global Real Estate Portfolio Initial Voya Russell Mid Cap Growth Index Portfolio Initial Voya Retirement Moderate Growth Portfolio Initial U.S

, 2000) A dose of 8mg astaxanthin has been demonstrated to decrease lipid peroxidation in 40 healthy males supplemented over a period of 12 weeks

Parkin, DJ-1, ubiquitin C-terminal hydrolase isozyme L1 (UCH-L1), nuclear receptor-related factor 1, and -synuclein are genes linked to either Parkinson- or Parkinson-related diseases