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Tumor Suppression: In rats with M-1 sarcoma, it inhibited tumor growth and induced "hemorrhagic necrosis" of the tumor mass

Francisco Triana-Martnez et al., in their research, administered gemcitabine alone (25 mg/kg, IP), digoxin alone (2 mg/kg, IP), or a combination of both drugs at the same doses through intraperitoneal injections to immunocompromised mice that had previously been subcutaneously injected with A549 lung adenocarcinoma cells [140]