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Botulinum neurotoxin type A (BoNT/A), an exotoxin from Clostridium botulinum, reversed the downregulation of type II collagen and the upregulation of MMP-13 induced by LPS in chondrocytes, alleviating LPS-induced chondrocyte toxicity, activating the SLC7A11/GPX4 antiferroptotic system, and enhancing mitochondrial function

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These findings also provide evidence for the ability of FES to improve the microenvironment after SCI

[DOI] [PubMed] [Google Scholar] 353.Li Q, Armstrong Z, MacRae A, Lenertz M, Feng L and Yang Z, Chem