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To further confirm the direct role of XKR8 in NET formation in vivo, we generated neutrophil-specific Xkr8 KO mice by crossing Xkr8 floxed mice ( Xkr8 fl/fl as the controls) with Ly6g cre KI mice, resulting in neutrophil-specific XKR8 KO mice ( Xkr8 fl/fl Ly6g cre ) (Extended Data Fig

Medler, 2015)

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