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Within the microglia, lactate is expected to enter the mitochondrial Krebs cycle, contributing to oxidative phosphorylation and hence producing high levels of ATP and forms of ROS, such as hydrogen peroxide, required for degradation of the invading pathogen

With the full view of TC metabolism, detecting and therapeutic strategies based on the reprogrammed metabolism in TC has developed quickly

This compound is supplied as a research-grade preparation intended for controlled laboratory use in analytical, biochemical, and in-vitro research applications

As heat stress induces ROS accumulation, we also studied the behavior of mutants affected in ROS metabolism