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In brief, the mice were administered a daily topical application of 62.5 mg of 5% imiquimod cream (Mingxinlidi, Sichuan, China) on their shaved backs for seven consecutive days

Selenoproteins related to fish antioxidant mechanism include GPXs, TXNRDs, SELENOP, SELENOS, and other selenoproteins, which regulate lipid metabolism, inflammatory damage, ROS and H 2 O 2 formation oxidative stress through antioxidant enzymes (SOD, GPX, and CAT) in fish antioxidant system

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Inhibitors of the proteasome stimulate the epithelial sodium channel (ENaC) through SGK1 and mimic the effect of aldosterone