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For instance, PPR significantly alters the pharmacokinetics of carbamazepine, increasing its maximum plasma concentration, half-life, and area under the curve by 68.7, 47.9, and 43.2%, respectivelyelevating risks of drug toxicity (85)

Should side effects persist beyond week two at any dose level, discussing your schedule with your PlexusDx provider may reveal an alternative timing strategy or the need for supportive medications that work better with morning or evening dosing

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Inhibition of GDH has been shown to suppress tumor growth in certain cancers, underscoring its critical role in cancer metabolism (77)