The F1-glutathione complex was found to be a non-competitive inhibitor, suggesting that the inhibitory binding site of F1-glutathione is different from the catalytic site of GST
In humans, oxidative stress is thought to be involved in the development of cancer, [3] Parkinson's disease, [4] Lafora disease, [5] Alzheimer's disease, [6] atherosclerosis, [7] heart failure, [8] myocardial infarction, [9] [10] fragile X syndrome, [11] sickle-cell disease, [12] lichen planus, [13] vitiligo, [14] infection, chronic fatigue syndrome, [15] and depression

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