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45,46 Increasingly, more studies have shown that G6PD activity is increased in several types of cancers, including bladder, breast, prostate, gastric cancers compared with normal tissues, and the high expression of G6PD predicts poor clinical outcome in various cancer patients and plays critical roles in tumorigenesis and chemoresistance

Neuroinflammation represents a critical axis of convergence and differentiation

Investigations are underway to see if dietary interventions (like ketogenic or Mediterranean diets) can beneficially remodel the PD microbiome