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Overall, tissue homeostasis is maintained within a bounded ROS window

Taking early, consistent action is crucial

South Dartmouth (MA): MDText.com, Inc

Energy metabolism and cortical spreading depression susceptibility Cortical spreading depression (CSD) is a neurophysiological phenomenon characterized by the strong depolarization of regional neurons or glial cells, spreading along the cortex to neighboring regions at a rate of 35 mm/min, ultimately leading to inhibition of neural activity (9)