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Treatment of NZB/W mice with an iron chelator deferiprone significantly delayed the onset of albuminuria and reduced blood urea nitrogen levels

These observations are in contrast to previous findings in the same Nrf2-GFP-HepG2 reporter model exposed to DEM or tert -butylhydroquinone, which indicate a lower Nrf2 response toward repeated treatments (Bischoff et al

This study examined the hypothesis that GSH-deficiency induces epigenetic alterations of VD metabolism genes, which can reduce the circulating 25(OH)VD 3 levels in obesity