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Obesity is a common disease in the senior citizen community due to a reduction in physical activity and a lack of access to good nutrition

In addition, serum levels of endotoxin, IL-6, IL-8, and IL-10 were significantly elevated in patients with stage I-IV CKD, while intestinal occludin and claudin-1 exhibited significant reduction in expression

In contrast, striatal iron exhibited a V-shaped time course with disease progression and MPTP stages, showing an initial decrease in de novo PD patients and asymptomatic animals, which was reversed in more advanced stages

When increased urination occurs, it typically reflects indirect factors such as improved blood glucose control, dietary changes, increased fluid intake, or co-prescribed medications like SGLT2 inhibitors or diuretics