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Description

Cytotoxic dolabellane diterpenes from the Formosan soft coral Clavularia inflata

OC(O)R 9

Although the downstream response to c-MET is common to many RTKs, the potency, endurance and specificity of c-MET-triggered pathways is secured by a network of upstream signaling co-receptors that physically associate with c-MET at the cell surface (Figure 3) [Trusolino et al