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[Abstract]2023 Feb;30(2):527-543

Gda takviyeleri T.C

Therefore, the object of the present invention is to provide a kind ofly to prepare the method for levocarnitine compound through chemical synthesis, is starting raw material with the 4-chloroacetyl acetacetic ester, uses L-tartrate and modifies Ni-B/SiO 2 As catalyzer, under the sodium hydroxide existence condition and Trimethylamine 99 reaction generate levocarnitine.The invention has the advantages that the catalyzer that provides a kind of price lower, improved the productive rate of levocarnitine greatly, reactions step is simple, and cost obviously reduces, and is more suitable for suitability for industrialized production

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