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have reported that a fully human anti-BMP6 antibody (KY1070), whether administered as monotherapy or in conjunction with Darbepoetin alfa, may enhance the effectiveness of anaemia treatment in chronic disease [99]

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The high sensitivity of mediator release from RBCs to mechanical force, such as deformation secondary to shear stress, has important implications for the conduct of investigation of the determinants of mediator release from RBCs in health and disease ( could be introduced through the measured lysis, conclusions about export will not be possible or must be qualified