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The NOX4-dependent protective effects are also supported by a study showing exacerbated damage by methyl vinyl ketone and acrolein, both major toxic constituents of tobacco smoke extract, in cells with impaired NOX4 signalling [80]

A new paper by researchers from the USA and China and published on the preprint server bioRxiv* in July 2020 discusses a new drug based on the catalase enzyme, which could play a vital part in reducing the inflammation associated with progressive and severe COVID-19 disease

This top-down control of metabolic protein expression and function through signal transduction and gene transcription is essential for establishing a framework through which biochemicals can be produced and consumed

Redox-active Se species inhibiting SARS-CoV-2 Mpro The Mpro of SARS-CoV-2, critical for viral replication, is a key target for therapeutic development (Reference Amporndanai, Meng and Shang81,Reference Mengist, Mekonnen and Mohammed82)