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Cardiovascular Disorders and Oxidative Stress Oxidative stress plays a pivotal role in cardiovascular diseases by contributing to the development of atherosclerosis, where plaque builds up in the arteries, reducing blood flow

Most experiments use young animals, ignoring the impact of aging, a core risk factor for OA, on mitochondria

Burwinkel B, Kreuder J, Schweitzer S, Vorgerd M, Gempel K, Gerbitz KD, Kilimann MW: Carnitine transporter OCTN2 mutations in systemic primary carnitine deficiency: a novel Arg169Gln mutation and a recurrent Arg282ter mutation associated with an unconventional splicing abnormality

Candidacy for this therapy is determined at COEM through individualized assessment, including laboratory evaluation and consultation with the medical team