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Stimulation by LPS and A induces microglial polarization towards the M1 phenotype, which involves significant reprogramming of glucose metabolism from OXPHOS to glycolysis, which is dependent on the mTOR-HIF-1 pathway

About 20% of people 65 and older have untreated tooth decay, and approximately half of US adults aged 30 and older have periodontitis (AAP 2015

Identification of neutrophil exocytosis inhibitors (Nexinhibs), small molecule inhibitors of neutrophil exocytosis and inflammation: druggability of the small GTPase Rab27a