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Hafidi ME, Buelna-Chontal M, Snchez-Muoz F, Carb R

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This stable E GSH observed in the nucleus and nucleoli throughout the cell cycle has important implications for cellular redox homeostasis, as these compartments host critical processes such as DNA replication, transcription, and ribosome biogenesis, all of which require finely tuned redox regulation

have designed ROS-scavenging and iron-chelating polymers with thioester and thioketal bonds to deliver Liproxstatin-1 (Lip-1), another radical-trapping antioxidant that inhibits ferroptosis, forming a triple therapeutic strategy for acute glaucoma