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supplementation may be beneficial Individuals with gastrointestinal conditions : Coeliac disease, Crohn's disease, or previous gastric surgery affect nutrient absorption Women with heavy menstrual periods : Increased iron requirements may necessitate supplementation Pregnant and breastfeeding women : Increased nutritional demands require careful dietary planning

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NNMT activity is also upregulated in the brain tissue of patients with Parkinson's disease (See e.g., K