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"Integrated genomic characterization of IDH1-mutant glioma malignant progression"

A boon for the vegetarians

For example, human induced pluripotent stem cell (iPS cell) astrocyte studies indicate that PSEN1 mutations enhance cytokine signaling via disrupted intramembrane proteolysis, lowering the threshold for astrocyte reactivity and predisposing cells to exaggerated inflammatory responses to modest stimuli 79