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Our observations suggest that pre-emptive genotyping of CYP2C9 and GSTM1 may aid in selection of more effective prophylaxis to reduce HC development in pediatric patients undergoing allogeneic HSCT

181 : 16611672 Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, Wang X

Among nonsteroidal anti-inflammatory drugs, aspirin dissociates mitochondrial-bound HK2 by disrupting its interaction with VDAC1, 1179 whereas diclofenac suppresses GLUT1 and HK2 activity, thus reducing glycolysis

Conclusions and future perspectives In conclusion, the multifaceted role of copper in atherosclerosis involves complex cellular and systemic metabolic processes