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Key mechanisms include: Activation of neurons in the area postrema and nucleus tractus solitarius in the brainstem Enhanced satiety signaling through distinct pathways from GLP-1 mechanisms Slowed gastric emptying via calcitonin receptor-mediated effects Reduced food reward signaling and decreased food noise through central appetite centers Studies in knockout mouse models confirmed that cagrilintides weight loss effects depend specifically on AMY1R and AMY3R presence, demonstrating receptor-specific mechanisms

Int J PharmTech Res 6:168173 Rahmani G, Farajdokht F, Mohaddes G, Babri S, Ebrahimi V, Ebrahimi H (2020) Garlic ( Allium sativum ) improves anxiety- and depressive-related behaviors and brain oxidative stress in diabetic rats

Dissolution of kaolinite induced by citric, oxalic, and malic acids

[DOI] [PubMed] [Google Scholar] 155.Giuffr M., Gazzin S., Zoratti C., Llido J.P., Lanza G., Tiribelli C., Moretti R