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Terutama pada orang dengan obesitas, suplemen ini berpotensi menurunkan massa lemak dan ukuran lingkar pinggang, meski hasilnya bervariasi

Gadalla and colleagues showed, as a proof of principle, a considerable improvement when neonatal Rett male mice were administered a gene therapy vector expressing the human MECP2e1 isoform by intracranial delivery (87)

demonstrated that higher plasma TMAO levels correlated with an increased risk of major adverse cardiovascular events (MACEs) during a 3-year follow-up in 4007 patients referred for elective coronary angiography

However, adverse side effects may be brought by inhibiting FMO3, including liver inflammation and trimethylaminuria (fish odour syndrome) (Wang et al., 2015)