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4) Comparative Efficacy Studies: Probiotic formulations should be compared against conventional SLE treatments to evaluate their relative effectiveness

Treatment with RBC@SeMSN@Uri reduced joint swelling to 2.53 mm at 72 h, comparable to the control group at 2.42 mm (Figures 6B, C)

F., Rajagopal, P., Jayaraman, S., et al

Reductions in cholesterol levels may diminish serotonin 5-HT1A receptor binding, disrupt G-protein coupling, and reduce the activity of the 5-hydroxytryptamine transporter (239, 240)