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Description

Interaction of acetaminophen with myeloperoxidase intermediates: optimum stimulation of enzyme activity

Two isoforms of this enzyme exist in mammalian cells: cytosolic CARS1 and mitochondrial CARS2, both of which have been identified as novel cysteine persulfide synthase (CPERS), possessing conserved cysteine persulfide-synthesizing activity across species [27,42] (Figure 3)