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PMID: 30890187 Acta Pharm Sin B Phenylalanine deprivation inhibits multiple myeloma progression by perturbing endoplasmic reticulum homeostasis

The seven additional Phase 3 readouts expected this year will provide the larger safety database the FDA needs to make this determination

(112) confirmed that gut microbiota-derived phenyl sulfate is an important contributor to albuminuria in diabetic kidney disease, suggesting that uremic toxin production and absorption can be reduced through modulation of gut microbiota metabolism

In vitro, manipulating cellular ROS has been found to slow fibroblast wound migration [115, 116] and to prevent the formation of postoperative adhesions in surgical animal models [112]