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2012;7:e35054

The 6-year DFS rate in the group of patients with present-GSTT1-GSTM1 genotypes was 65.7 and 87.1% in that of patients with null-GSTT1-GSTM1 genotypes (log-rank test, P =0.01)

The Journal of Nutritional Biochemistry, 24(8), 14151422

In aging, pathological mechanisms triggered by increased IOP will affect neuronal tissue which is less resistant to glaucomatous damage ( With aging, the lamina cribrosa becomes stiffer as a consequence of collagen deposition and alterations in elastin synthesis associated with stiffening and thickening of the astrocyte basement membranes and extracellular matrix, increasing the susceptibility of the optic nerve head to glaucomatous damage (Kotecha et al., 2006)