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[195] [212] This internalization is mediated by RhoA activation and its downstream effector ROCK, a process that is TAAR1-dependent

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Although T RM cells play a vital role in protecting the immune system from pathogens, dysregulation of these cells can result in excessive inflammation and tissue damage in IBD

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Excessive extracellular glutamate inhibits system Xc , reducing cystine uptake and depleting GSH, thereby promoting ferroptosis

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