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37,38 Sympathetic signaling activates the hypothalamic-pituitary-adrenal (HPA) axis, a network that connects the nervous system to the adrenal glands and controls their release of the bodys primary stress hormone, cortisol

(PubMed) Green R, Miller JW

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How long the injection lasts depends on several factors: How severe the deficiency is A persons age and how fast their body processes things Problems with digestion or absorbing nutrients Daily habits or activity levels How often does the body use B12 inside its cells People with pernicious anemia or ongoing deficiency often get weekly shots, while others do fine with a monthly injection