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The cytosolic 46-kDa -tocopherol-associated protein (-TAP) regulates the intracellular distribution of vitamin E (Stocker et al., 1999, Zimmer et al., 2000)

4.1 Clinical relevance of the CLP model The CLP model was selected for its unique ability to recapitulate core clinical features of SAE: polymicrobial sepsis, hippocampal neurodegeneration, and chronic cognitive impairment ( 4.2 Microglia-mediated oxidative neuronal injury Microglial activation initiates neuronal damage, and a previous study revealed that the microglial inhibitor minocycline reduces neuronal apoptosis ( in vivo oxidative stress ( Mechanistically, a microglial inflammation-oxidative stress feedforward loop perpetuates injury: Activated microglia secrete neurotoxins, impairing neuronal mitochondrial function and antioxidant capacity (such as GPX4), thus increasing ROS leakage

If your white spots are infrequent, and you think theyre likely related to injury, you may not need to see a doctor

Physiol Rev (1978) 58(2):31796