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Together, these results clearly indicated a functional metabolic switch from mitochondrial respiration to glucose-dependent metabolism in CD8 + Tc during SARS-CoV-2 infection

The compensation in GSH metabolism was not sufficient, however, to completely protect against a parkin deficiency-linked rise in radicals, as seen by the trend for more nitrotyrosinated proteins and the significant rise in total carbonyl content in the brain (Figs