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Selenium deficiency has been associated with Th2 cell response, whereas higher selenium levels favour Th1 response (193)

10.1161/CIRCULATIONAHA.108.815043 129 WangJ.ShiJ.WeiJ.WangJ.GaoK.LiX.et al (2017)

These mutations disrupt electron transfer between complex Is Fe-S center and CoQ10, causing excessive reduction of Fe-S clusters, electron leakage, and increased production of oxygen radicals ( External factors like immune responses and inflammation often induce mitochondrial oxidative damage