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Diagnosis of pulmonary embolism during pregnancy: a multicenter prospective management outcome study

In a clinical trial half of patients receiving a 200mg dose followed by 100mg dose 2 weeks later were experiencing a clinical response to the drug at 6 weeks, with 18% in clinical remission

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Researched effects In a diet-induced-obese mouse study (Neelakantan et al., Biochemical Pharmacology, 2018), subcutaneous 5-Amino-1MQ (20 mg/kg, three times daily, roughly 11 days) produced about 5.1% body-weight loss versus continued weight gain in untreated controls, roughly 35% less epididymal white fat mass, smaller adipocytes, lower plasma cholesterol, and improved glucose tolerance, with no reported change in food intake and no observed adverse effects in the mice