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Potential therapeutic strategies focus on reducing oxidative damage and modulating iron metabolism (183, 184)

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In Arabidopsis , ONOO - could induce hypersensitive response (HR) and defense-related gene expression ( 2 ) to one of the two equivalent ortho carbons of the aromatic ring of Tyr residues and metal nitrosylation, was reported as a new important RNS-mediated post-translational modification (Saito et al., 2006

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