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Thirdly, inhibiting ferroptosis as a therapeutic approach may have potential side effects since this RCD mechanism also plays an essential role in normal physiological processes

doi: 10.1136/gutjnl-2021-325989 64 IqbalNTKhanHKhalidAMahmoodSFNasirNKhanumIet al

After treatment completion, there was a decrease of HouseBrackmann scores in all patients (Fig

CAFs are major regulators of tumor metabolic remodeling and affect cancer cell growth, drug resistance and immune escape through multiple metabolic pathways, such as glucose, amino acid and lipid metabolism [321]