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Under these conditions, citrulline, a byproduct of nitric oxide synthesis, can recover arginine via the arginine-citrulline pathway

Vyas J, Muirhead N, Singh R, Ephgrave R, Finlay AY

Single-cell RNA sequencing analysis identifies enhanced expression of senescence-associated secretory phenotype genes, elevated p16 protein levels, and increased -galactosidase-positive cells in keloid tissue compared to normal skin

A: Alternatives to estradiol patches include FDA-approved transdermal gels and sprays, oral estradiol (with a different clot-risk profile), vaginal estrogen preparations for genitourinary symptoms, and compounded transdermal estradiol creams from PCAB-accredited pharmacies