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Certain medical conditions and medications increase B12 requirements: Long-term use of metformin (diabetes medication) or proton pump inhibitors (PPIs for acid reflux) can impair B12 absorption [13] [14] Gastrointestinal conditions such as Crohn's disease, coeliac disease, or previous gastric surgery Autoimmune conditions beyond pernicious anaemia may affect B12 metabolism When to contact your GP : If you are taking B12 supplements or receiving injections but continue to experience symptoms, request a review

You can order on Monday morning and confidently plan reconstitution for Wednesday or Thursday

In contrast, the only significant change among non-responders was in the vitamin B12 levels

This also illustrates why residents have been complaining of red or discolored water after the switch to the Flint River source