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however, there were important limitations to consider, including small sample sizes, a lack of long-term observation, the use of a single species or strain, the lack of in-depth exploration of cellular or molecular mechanisms, failure to assess other aspects of reproductive function, a lack of validation of the clinical relevance, and a failure to consider individual differences in drug dosages

found that Que intake resulted in a 39% reduction in hepatic TG content and a 1.5-fold increase in VLDL in HFD-induced NAFLD rats ( in vivo and vitro and showed a significant decrease in serum transaminase levels, a recovery for liver superoxide dismutase, catalase and GSH levels, and a relieve in lipid accumulation ( via Que supplementation in mice

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