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PMID: 33721187 GeneRegulatory effect and mechanism of APN gene on porcine epidemic diarrhea virus resistance

Advances in nutrition (Bethesda, Md.), 5(5), 503514

-synuclein delays mitophagy by targeting the N-terminus of Miro, leading to excessive and abnormal Miro accumulation on the mitochondrial surface 16

No long-term human dose-response desensitization study exists for either peptide, but the mechanism is real and users relying on twice-daily or three-times-daily injection schedules indefinitely are working against basic receptor pharmacology