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GO_BP analysis revealed that many of the downregulated host proteins were associated with metabolic or catabolic, such as catabolic process ( p adjusted = 1.6E-16, 71 proteins, 37.8%), small molecule metabolic process ( p adjusted = 1.1E-11), and organic substance catabolic process ( p adjusted = 2.0E-14)

The position of these 5'-bound fragments correlated closely with the 5'-most exon-intron junction of the pre-mRNA

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Choline is also a key precursor in the production of acetylcholine, the neurotransmitter which regulates the forming of memories, recall of information, the ability to focus, verbal reasoning, and some math skills