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doi: 10.1007/s10295-002-0014-0 115 KangS.LeeY

New reports reveal that in cancers expressing wtp53, such as melanoma, its overactivation favors a slow-cycling phenotype, a population characterized by low proliferation but higher invasive capabilities that result in pharmacological resistance

This pathological NO, and its potent derivative peroxynitrite (ONOO ), inhibit mitochondrial respiratory complexes, contributing to bioenergetic failure or cytopathic hypoxia (45)

Dopamine D2 and D3 receptor occupancy in normal humans treated with the antipsychotic drug aripiprazole (OPC 14597): a study using positron emission tomography and [11C]raclopride