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Description

There are 497 human genes that encode a cofactor-dependent enzyme, of which at least 193 (39%) reportedly harbor disease-causing variants [69, 70] (Additional file 8 : Table S6)

They found that at the highest dosage of 4.8 mg survodutide weekly, study participants lost 14.9% of their body weight in comparison with a placebo group (2.8% weight loss) [122]