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Cell Mol Life Sci (2022) 79(5):228

doi: 10.1183/16000617.0241-2021 125 GrayRDHardistyGReganKHSmithMRobbCTDuffinRet al

The top 3 negatively enriched HALLMARK terms in high IGF-1 subgroups were epithelial mesenchymal transition, KRAS upsignaling, and allograft rejection ( Figure 8C ), and the top positively enriched HALLMARK terms were MYC targets V2, reactive oxygen species pathway, oxidative phosphorylation, and DNA repair ( Figure 8D )