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Some medical conditions that can cause sciatica include herniated discs, lumbar spinal stenosis, piriformis syndrome, spondylolisthesis, degenerative disc disease, diabetes, tumors, and trauma

and 51+ years, 1.5 mg

The peptide's mechanism involves disrupting the FOXO4-p53 interaction specifically in replication-stressed senescent chondrocytes, triggering selective apoptosis while preserving healthy proliferative cells needed for cartilage formation