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However, its results should ideally be compared with those from HAT-based assays, as discrepancies may arise due to chemical variability among diverse sample types and differences in reactivity rates for various compounds in the assay

2014;9(1):e82331

very high doses, non-medical settings)

In this review, we will systematically summarize the recent progress in amino acid metabolism in the context of cancer and the tumor microenvironment, describe their interconnection or indispensable role in cancer growth, epigenetic modification, cancer immunity, and ferroptosis, and discuss the potential therapeutic applications for targeting amino acid metabolism