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The core mechanism lies in that copper ions, after being reduced by ferridoxin (FDX1), directly target and induce the oligomerization of the acylated tricarboxylic acid (TCA) cycle enzyme, thereby triggering fatal protein toxic stress

9 For example, one longitudinal study reported that probable RBD symptoms disappeared in only 7.5% of PD patients during a four-year follow-up

doi: 10.1016/j.jplph.2007.01.017 43 EltayebA

Most of the evidence on BPC-157 which is based on a peptide found in human stomach juices comes from preclinical work involving animals, and is quite limited for humans