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Furthermore, overexpression of hypoxia-inducible factor 1- (HIF-1), VEGF and platelet-derived growth factor subunit A (PDGF-A) are detected in GBM cells holding IDH mutation (115117)

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The headache of gathering all these materials is admittedly a drawback for some researchers, as there are not many quality vendors that carry them

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No cytokine-targeting agents or anti-inflammatory treatments have demonstrated substantial efficacy, and certain interventions have led to higher mortality rates

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